一、个人简介

李慧芳，女，博士，硕士生导师。2017年6月获中国海洋大学硕士学位，2021年8月在厦门大学近海海洋环境国家重点实验室获得博士学位，2021年8月至今为江苏海洋大学校聘副教授。

目前主持国家自然科学基金-青年科学基金项目、连云港市博士后基金和江苏省自然资源部滨海盐沼湿地生态与资源重点实验室课题等项目，参与国家基金重大研究计划-重点项目、面上项目及欧盟委员会项目（EU-Horizon 2020）多项。入选江苏省科技副总，连云港市“花果山英才计划”-双创博士。近年来一直从事于海洋中病毒生态学及水产养殖病害防治研究。已在Microbiology Spectrum、Environmental Microbiology、Journal of Geophysical Research: Oceans、Frontiers in microbiology、Communications Biology等权威刊物发表SCI论文16篇。

E-Mail: huifangli@jou.edu.cn

通讯地址：江苏省连云港市苍梧路59号江苏海洋大学海洋科学与水产学院

二、研究方向

通过微生物学、生态学、海洋学等技术手段，研究近岸及大洋环境中海洋病毒的生物地理学分布、多样性及其与宿主相互作用；

水产养殖病害防治（噬菌体治疗和海洋来源的活性天然产物）。

三、研究教育经历

2015.09-2017.06，中国海洋大学，硕士；

2017.09-2021.08，厦门大学，博士。

四、工作经历

2024.01-，海洋科学与水产学院，生物科学与技术系，系副主任；

五、代表性科研项目

1. 南海季风爆发对浮游病毒和浮游细菌多样性的影响，国家自然科学基金-青年科学基金项目，项目编号：42206133，2023.01-2025.12，主持；

2. 海州湾浮游病毒生态动力学和多样性，连云港市博士后基金，项目编号：LYG2022003, 2022-2024，主持；

3、病毒驱动的深部生物圈碳循环机制与过程，国家自然科学基金委-重大研究计划-重点支持项目，项目编号：91951209，2020.01-2023.12，参与；

4、The future of Arctic coastal ecosystems - Identifying transitions in fjord systems and adjacent coastal areas (FACE-IT)，欧盟委员会，项目编号：869154，HORIZON 2020，参与。

5、江苏省自然资源部滨海盐沼湿地生态与资源重点实验室开放课题（2022-2024），主持。

六、代表性科研论文

1. Li Huifang, Cai Lanlan, Wang Long, Wang Yu, Xu Juntian & Zhang Rui* (2024) The structure and assembly mechanisms of T4-like cyanophages community in the South China Sea. Microbiology Spectrum 12: e0200223.

2. Zhang Di, Feng Yao, Chu Mingyi, Dai Yujiang, Jiang Lu & Li Huifang* (2024) Anti-vibriosis bioactive molecules from marine-derived variant Streptomyces sp. ZZ741A. Natural Product Research 1-12.

3. Cai Lanlan, Xu Bu, Li Huifang, Xu Yongle, Wei Wei & Zhang Rui* (2023) Spatiotemporal shift of T4-like phage community structure in the three largest estuaries of China. Microbiology Spectrum 11: e05203-e05222.

4. Li Huifang, Liu Lu, Wang Yu, Cai Lanlan, He Maoqiu, Wang Long, Hu Chen, Jiao Nianzhi & Zhang Rui* (2021) T4-like myovirus community shaped by dispersal and deterministic processes in the South China Sea. Environmental microbiology 23: 1038-1052.

5. Li Huifang, Gao Jie, Ma Shiyun, Xiao Rongda, Zhou Xing, Feng Wanting, Zhao Siyu, Luo Jiaqi & Zhang Di* (2023) Isolation and genome sequencing of a novel lytic Pseudoalteromonas phage SL20. Marine Genomics 71: 101048.

6. Zhou Xing, Gao Jie, Xiao Rongda, Qiao Yifan, Zhu Yuang, Zhang Di, Zhang Xinyu, Li Huifang* & Xu Juntian* (2023) Characterization and genomic analysis of a novel Pseudoalteromonas phage PS_L5 Marine Genomics 72: 101069.

7. Zhang Di, Feng Yao, Li Huifang* & Zhang Zhizhen* (2023) Bioactive Secondary metabolites produced by the hadal actinomycete Streptomyces sp. SY1414 isolated from the Mariana Trench-derived sediment. The Natural Products Journal 14: e281123223928.

8. Zhang Di, Zheng Jinyang, Chu Mingyi, Feng Yao & Li Huifang* (2023) Secondary metabolites from the endophytic fungus Cladosporium sp. ZLM-6. Biochemical Systematics and Ecology 111: 104741.

9. Guo Jiachen, Yang Jjin, Wang Pei, Guo Bo, Li Huifang, Zhang Di*, An Faliang* & Gao Song* (2023) Anti-vibriosis bioactive molecules from Arctic Penicillium sp. Z2230. Bioresources and Bioprocessing 10:11.

10. Li Yan#, Li Huifang#, Jiang Yong, Shao Hongbing, He Hui* & Wang Min* (2022) Isolation and complete sequence of one novel marine bacteriophage PHS21 infecting Pseudoalteromonas marina. Current microbiology 79: 213.

11. Li Xiaolin*, Wu Kai, Gu Shuai, Jiang Peng, Li Huifang, Liu Zhanfei & Dai Minhan (2021) Enhanced biodegradation of dissolved organic carbon in the western boundary Kuroshio Current when intruded to the marginal South China Sea. Journal of Geophysical Research: Oceans 126: e2021JC017585.

12. Yang Yunlan#, Zhang Fei#, Chen Xiaowei, Li Huifang, Jiao Nianzhi* & Zhang Rui* (2021) Insignificant response of bacterioplankton community to elevated pCO2 during a short-term microcosm experiment in a subtropical eutrophic coastal ecosystem. Frontiers in Microbiology 12: 730377.

13. Zhang Rui*, Li Yanxia, Yan Wei, Wang Yu, Cai Lanlan, Luo Tingwei, Li Huifang, Weinbauer Markus G. & Jiao Nianzhi (2020) Viral control of biomass and diversity of bacterioplankton in the deep sea. Communications Biology 3: 256.

14. Liu Zhaoyang#, Li Huifang#, Wang Min*, Jiang Yong*, Yang Qingwei, Zhou Xinhao, Gong Zheng, Liu Qian & Shao Hongbing (2018) Isolation, characterization and genome sequencing of the novel phage SL25 from the Yellow Sea, China. Marine Genomics 37: 31-34.

15. Li Huifang, Liu Zhaoyang, Wang Min*, Liu Xinxin, Wang Qi, Liu Qian, Jiang Yong*, Li Zhongshi, Shao Hongbin & McMinn Andrew (2019) Isolation and genome sequencing of the novel marine phage PHS3 from the Yellow Sea, China. Marine Genomics 44: 70-73.

16. Liu Qian, Lu Borong, Song Xue, Li Yan, Gao Yu, Li Huifang Wang Min, Shao Hongbing, Warren Alan, Chen Xiangrui*, Jiang Yong*, Lin Zhihua. (2017) Recovery of ciliated protozoan communities in response to environmental change in a shrimp-farming pond in southern China. Journal of the Marine Biological Association of the United Kingdom 98: 1263-1272.