房耀维,男,博士,教授,研究生导师,江苏海洋大学科技处副处长。加州大学圣地亚哥分院Scripps海洋研究所访问学者。国家自然科学基金评审专家、教育部学位论文评审专家、江苏省食品学会青年委员会副秘书长,江苏省微生物学会理事,江苏省药学会海洋药物专业委员,食品工业科技青年编委,江苏省 “333高层次人才培养工程”第三层次培养对象,江苏省 “六大人才高峰”高层次人才,江苏省“青蓝工程”优秀青年骨干教师培养对象,连云港市“521高层次人才培养工程”第二层次培养对象,“苏北发展特聘专家”。主持国家自然科学基金面上项目、江苏省自然科学基金、江苏省 “ 333 工程”科研项目、江苏省 “六大人才高峰”高层次人才项目、教育部留学回国人员科研启动基金、中国博士后科学基金等省部级项目。获得江苏省科技进步奖三等奖、中国轻工业联合会科学技术发明奖三等奖、江苏省轻工业科学技术奖励技术发明奖一等奖、江苏省轻工业科学技术奖励技术发明奖三等奖各1项。在Green Chemistry、Carbohydrate Polymers等期刊发表论文150余篇,SCI收录50余篇;授权国家发明专利 7 件;参与出版专著1部。
研究方向:海洋生物资源开发及利用
联系方式:15861240818 Email:foroei@163.com
二、教学情况
承担研究生留学生《Food iotechnology》《Preparation Technology of Marine natural Product》和本科生《微生物学》、《酶工程》等课程的教学工作;指导研究生多名。
三、科研情况
(一)代表性论文
1. Liu Q, Liu S, Ye Q, Hou X, Yang G, Lu J, Hai Y,Shen J,Fang Y*. A Novel Streptococcus thermophilus FUA329 isolated from Human breast milk capable of producing Urolithin A from ellagic acid. Foods 2022, 11, 3280. (SCI 2区, IF 5.561).
2. Yang G, Hou X, Lu J, Wang M, Wang Y, Huang Y, Liu Q, Liu S*, Fang Y*. Enzymatic modification of native chitin and chitin oligosaccharides by an alkaline chitin deacetylase from Microbacterium esteraromaticum MCDA02. Int J Biol Macromol. 2022 Apr 1;203:671-678. doi: 10.1016/j.ijbiomac.2022.01.167 (SCI 2区, IF 11.60).
3. Mi H, Liu S, Hai Y, Yang G, Lu J, He F, Zhao Y, Xia M, Hou X*, Fang Y*. Lactococcus garvieae FUA009, a Novel Intestinal Bacterium Capable of Producing the Bioactive Metabolite Urolithin A from Ellagic Acid. Foods. 2022, 11(17):2621 (SCI 2区, IF 5.561).
4. Ding Z, Ahmed S, Hang J, Mi H, Hou X, Yang G, Huang Z, Lu X, Zhang W, Liu S, Fang Y*. Rationally engineered chitin deacetylase from Arthrobacter sp. AW19M34-1 with improved catalytic activity toward crystalline chitin. Carbohydr Polym. 2021, 274: 118637. (SCI 1区, IF 10.723).
5. Guang Yang, Xiaolin Cui, Shu Liu, Jing Lu, Xiaoyue Hou, Wenrong Meng, Bofei Wu, Yongcheng Su, Hongyu Zhang, Wei Zheng*, Yaowei Fang *. Effects of dietary Lactobacillus helveticus on the growth rate, disease resistance and intestinal health of pond loach (Misgurnus anguillicaudatus) [J]. Aquaculture, 2021, 544: 737038. (SCI 1区, IF 5.135).
6. Xincai Wu, Sibtain Ahmed, Xiaolin Cui, Jiahao Hang, Shujun Wang, Shu Liu, Yaowei Fang*. Expression and characterization of a novel organic solvent tolerant protease from Bacillus sphaericus DS11. Preparative Biochemistry Biotechnology, 2021, 51(1): 28–34. (SCI 4区, IF 2.30).
7. Shu Liu, Sibtain Ahmed⁎, Chunguang Zhang, Tongxiao Liu, Changlun Shao, Yaowei Fang*. Diversity and antimicrobial activity of culturable fungi associated with sea anemone Anthopleura xanthogrammica. Electronic Journal of Biotechnology. 2020, 44: 41-46 (SCI 4区, IF 2.47).
8. Jinong Chai, Jiahao Hang, Chunguang Zhang, Jie Yang, Shujun Wang, Shu Liu*, Yaowei Fang*. Purification and characterization of chitin deacetylase active on insoluble chitin from Nitratireductor aquimarinus MCDA3-3. International Journal of Biological Macromolecules. 2020, 152: 922-929 (SCI 2区, IF 4.04).
9. Shu Liu, Sibtain Ahmed*, Yaowei Fang*. Cloning, Expression and Characterization of a Novel αAmylase from Salinispora arenicola CNP193. The Protein Journal. 2019, 38: 716–722. (SCI 4区, IF 1.22).
10. Wenbo Ye, Huazhong Ma, Liang Liu, Juan Yu, Jiangli Lai, Yaowei Fang*, Yimin Fan*. Biocatalyzed route for the preparation of surface-deacetylated chitin nanofibers. Green chemistry, 2019, 21, 3143-3151 (SCI 1区, IF 9.43).
11. Zhanghui Gu, Jiangli Lai, Jiahao Hang, Chunguang Zhang, ShujunWang, Yuliang Jiao, Shu Liu*, Yaowei Fang*. Theoretical and experimental studies on the conformational changes of organic solvent-stable protease from Bacillus sphaericus DS11 in methanol/water mixtures. International Journal of Biological Macromolecules, 2019, 128: 603–609 (SCI 2区, IF 4.04).
12. Xiaofeng Mou, Xinliu, Rufang Xu, Meiyan Wei, Yaowei Fang*, Changlun Shao*. Scopuquinolone B, a new monoterpenoid dihydroquinolin-2(1H)-one isolated from the coralderived Scopulariopsis sp. Fungus. Natural Product research, 2018, 32(7): 773–776. (SCI 3区, IF 1.93).
(二)承担科研项目
1. 企业横向 转化鞣花酸生成尿石素A菌株的筛选及初步应用,JOUH21336, 2022-7至2023-06,在研,共同主持;
2. 江苏省教育厅,江苏省高等学校自然科学研究重大项目,20KJA550001,构巢曲霉几丁质脱乙酰酶抑制剂的筛选及分子机制研究,2020-2023,在研,主持;
3. 国家自然科学基金面上项目:海洋Bacillus sphaericus蛋白酶有机溶剂耐受性的分子机制研究(31772016),2018-2021;
4. 江苏省省海洋科技创新项目:水产养殖网箱的污染防治及污染物快速清除关键技术研究( HY2018-10),2018-2020
5. 江苏省第十三批“六大人才高峰”高层次人才项目:海洋专性放线菌Salinispora arenicola新颖酶基因的发掘及表达研究(2016-SWYY-195),2016-2018。
(三)获得专利
1. 来自海洋的解角质素微杆菌MCDA02及其产酶方法与产品,ZL201710272763.5
2. 快速筛选分泌耐有机溶剂蛋白酶微生物的方法,中国发明专利公开号:ZL201210127417.5
3. 快速筛选分泌耐有机溶剂脂肪酶的海洋微生物的方法,中国发明专利公开号:ZL201210127453.1。